Prosaposin (PS) is a secretory neurotrophic factor, as well as a regulator of lysosomal enzymes.We previously reported the up-regulation of PS and the possibility of its axonal transport by GABAergic interneurons after exocitotoxicity induced by kainic acid (KA), a glutamate analog.In the present lg gbb72mbubn study, we performed double immunostain
Summary.Hand elevation is a common recommendation for the treatment of hand injuries to combat development of painful swelling.However, noncompliance with elevation after hand procedures is common, and this is due in part to the lack of acceptable orthotics to assist in this elevation.Conventional slings are often not recommended due to potential e
The purpose of this review is to discuss recent findings related to sex differences in behavioral dyscontrol that lead to drug addiction, and clinical implications for humans are discussed.This review includes research conducted in animals and humans that reveals fundamental aspects of behavioral dyscontrol.The importance of sex differences in aspe
The link between anger and bodily states is readily apparent kt-swled45ps-4a-8csa-vdim-p based on the autonomic and behavioral responses elicited.In everyday life angry people react in different ways, from being agitated with an increased heart rate to remaining silent or detached.Neuroimaging evidence supports the role of mid-posterior insula and
Darcy Gillis,1 Jillian Demmons,1 Graeme Rocker1,2 1Division of Respirology, Department of Medicine, Queen Elizabeth II Health Sciences Centre, Nova Scotia Health Authority, Halifax, NS, copyright; 2Division of olea europaea montra Respirology, Nova Scotia Health Authority, Dalhousie University, Halifax, NS, copyright Background: The Halifax-based I